Assessment of fibroblast growth factor 19 as a non-invasive serum marker for hepatocellular carcinoma

Table 6 Diagnostic performance of fibroblast growth factor 19 and alpha fetoprotein for differentiation of hepatocellular carcinoma cases

	Cut-off point	AUC	Sensitivity	Specificity	PPV	NPV
FGF-19	> 180 pg/mL	0.98	100%	90%	90%	100%
AFP	> 8.2 ng/mL	0.78	63.33%	83.33%	79.2%	69.4%

AFP: Alpha fetoprotein; AUC: Area under the curve; FGF-19: Fibroblast growth factor 19; HCC: Hepatocellular carcinoma; NPV: Negative predictive value; PPV: Positive predictive value.