Hepatic involvement in children with acute bronchiolitis

Table 2 Results of laboratory investigations in the 166 children who presented with acute bronchiolitis

Variable	Normal range	Mean	SD	Median	Minimum	Maximum	Tested patients (%)
White blood cell count (× 109/L)	3.6-9.6	10.8	5.4	9.7	0.80	27.8	166 (100)
Hemoglobin level (g/dL)	12.0-14.5	11.5	2.3	11.0	5.7	20.0	166 (100)
Platelet count (× 109/L)	150-400	410	179.7	383.5	14.5	971.0	166 (100)
Total serum protein (g/L)	64-82	57.8	8.7	58.0	25.0	96.0	161 (97)
Serum albumin (g/L)	38-54	41.5	10.7	41.0	17.0	143.0	161 (97)
Serum globulin (g/L)	15-30	18.0	10.7	17.0	6.0	140.0	161 (97)
Total bilirubin (µmol/L)	5-21	37.4	61.2	10.0	2.0	482.0	161 (97)
Direct bilirubin (µmol/L)	0-5	12.0	14.4	11.0	1.0	122.0	71 (42.8)
Indirect bilirubin (µmol/L)	< 18	56.0	46.0	27.0	1.0	454.0	71 (42.8)
Alkaline phosphatase (U/L)	150-420	242.6	141.7	198.0	58.0	841.0	161 (97)
Alanine aminotransferase (U/L)	< 41	25.6	30.2	19.0	6.0	247.0	161 (97)
Gamma glutamyl transferase (U/L)	< 18	63.2	80.0	32.0	6.0	526.0	145 (87.3)
Prothrombin time	10-14	13.7	2.8	12.9	9.5	25.2	46 (27.7)
INR	0.6-1.2	1.1	0.3	1.1	0.79	2.2	46 (27.7)
PTT (sec)	28-43	28.2	9.7	26.8	13.2	63.3	46 (27.7)
Fibrinogen (mg/dl)	217-496	285.9	213.8	233.8	0.0	1115.2	34 (20.48)
Thrombin time (sec)	15.6 -18.4	17.9	4.1	17.3	4.1	13.0	33 (19.87)
Random blood sugar (mmol/L)	3.6-8.9	5.7	1.4	5.2	4.0	10.0	53 (32)
Ammonia (µmol/L)	11-35	80.6	61.2	62.0	7.0	230.0	11 (6.6)
Lactic acid (mmol/L)	0.5-2.2	3.1	3.3	1.5	1.0	10.0	7 (4.2)
Lactate dehydrogenase (units/L)	250-650	1030.1	1281.9	531.5	3.0	3509.0	6 (3.6)
Iron profile (µg/dL)	11.6-31.3	9.4	5.7	8.0	4.0	19.0	9 (5.4)
CRP (mg/L)	0.3	26.8	39.2	9.5	10.0	297.0	166 (100)

SD: Standard deviation; INR: International normalized ratio; PTT: Partial thromboplastin time; CRP: C-reactive protein.