Correlation of hepatitis B surface antigen expression with clinicopathological and biochemical parameters in liver biopsies: A comprehensive study

Figure 1 Different staining patterns of hepatitis B surface antigen in liver tissues. A: Dense cytoplasmic staining in many discrete hepatocytes; B: Diffuse but faint cytoplasmic staining in discrete hepatocytes; C: Diffuse faint cytoplasmic staining in a group of hepatocytes near an inflamed portal area; D: Globular and spotty staining in discrete and in a small group of hepatocytes; E: Submembranous staining in a large group of cells; F: Membranous expression of hepatitis B surface antigen. Original magnifications A and C × 200, B, D, E and F × 400, counter-stained with Mayer’s hematoxylin.