Assessment for the minimal invasiveness of laparoscopic liver resection by interleukin-6 and thrombospondin-1

Table 5 Univariate and multivariate analysis of factors that related with lower level of thrombospondin-1 on postoperative day 1 in 30 patients who has undergone hepatectomy

Factors	Univariate analysis			Multivariate analysis
	OR	95% CI	P	OR	95% CI	P
Sex (male/female)	0.57	0.12-2.48	0.46
Age (≥ 75/< 75, yr)	1.00	0.23-4.26	1.00
Higher level of IL-6 on POD1 (≥ 17.0/< 17.0, pg/mL)	5.50	1.22-29.4	0.03	5.32	1.08-32.2	0.04
Operative method (OLR/LLR)	3.50	0.73-20.3	0.29
Number of tumor (single/multiple)	1.00	0.23-4.39	1.00
Operative time (< 369/≥ 369, min)	0.33	0.07-1.43	0.14
Bleeding loss (< 443/≥ 443, ml)	0.44	0.10-1.88	0.27
Complication (yes/no)	1.63	0.23-14.0	0.62
Skin incision (reverse L-sharp/others)	4.57	0.97-26.7	0.05	4.38	0.82-29.9	0.09
Liver mobilization (yes/no)	3.24	0.56-26.2	0.19

TSP-1: Thrombospondin-1; IL-6: Interleukin-6; OR: Odds ratio; CI: Confidence interval; OLR: Open liver resection; LLR: Laparoscopic liver resection.