Assessment for the minimal invasiveness of laparoscopic liver resection by interleukin-6 and thrombospondin-1

Table 4 Univariate and multivariate analysis of factors that related with higher level of interleukin-6 on postoperative day 1 in 30 patients who has undergone hepatectomy

Factors	Univariate analysis			Multivariate analysis
	OR	95%CI	P	OR	95%CI	P
Sex (male/female)	0.80	0.18-3.50	0.77
Age (≥ 75/< 75, yr)	1.289	0.30-5.57	0.73
Operative method (OLR/LLR)	9.33	1.74-75.7	0.008	7,48	1.28-63.3	0.02
Number of tumors (single/multiple)	0.21	0.04-0.99	0.048	0.29	0.04-1.64	0.16
Operative time (< 369/≥ 369, min)	2.31	0.54-10.7	0.29
Bleeding loss (< 443/≥ 443, mL)	3.00	0.70-14.3	0.14
Complication (yes/no)	0.74	0.20-11.9	0.74
Skin incision (reverse L-sharp/others)	1.94	0.43-9.62	0.39
Liver mobilization (yes/no)	1.73	0.31-10.6	0.53

IL-6: Interleukin-6; OR: Odds ratio; CI: Confidence interval; OLR: Open liver resection; LLR: Laparoscopic liver resection.