Epigenetic mechanisms of liver tumor resistance to immunotherapy

doi:10.4254/wjh.v13.i9.979

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Sep 27, 2021 (publication date) through Jul 6, 2024

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Sep 27, 2021; 13(9): 979-1002
Published online Sep 27, 2021. doi: 10.4254/wjh.v13.i9.979

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Figure 4 Overview of the main epigenetic mechanisms in hepatocellular carcinoma and their inhibitors. Made with biorender.com. A: DNA methylation; B: Histone modification. DNMT: DNA methyltransferase; TET: Ten-eleven translocation; DNMTis: DNA methyltransferase inhibitors; HAT: Histone acetyl transferase; HDAC: Histone deacetylase; HDACis: Histone deacetylase inhibitors; HMT: Histone methyl transferase; HDM: Histone demethylase; HMTis: Histone methyl transferase inhibitors; HCC: Hepatocellular carcinoma.

Citation: Sanceau J, Gougelet A. Epigenetic mechanisms of liver tumor resistance to immunotherapy. World J Hepatol 2021; 13(9): 979-1002
URL: https://www.wjgnet.com/1948-5182/full/v13/i9/979.htm
DOI: https://dx.doi.org/10.4254/wjh.v13.i9.979