Development of a risk score to guide targeted hepatitis C testing among human immunodeficiency virus patients in Cambodia

Table 1 Harm and benefit of hepatitis C virus testing and not testing

Harm of testing (false positives)	Benefit of testing	Harm of not testing (false negatives)	Benefit of not testing
Low, but existing:	High (for some):	High (for some):	Important in some contexts:
Cost of tests, human resources (lab & counseling)	If diagnosed positive: good treatment available (high cure rate, few side effects, short /life-saving for cirrhotic patients/ but treatment often not urgent)	Denial of live-saving, highly efficacious and affordable treatment	Cost-saving in resource-constrained environment with many competing interests
Stress related to waiting for results	Impact on further transmission (but less weight in HCV populations with low risk profile)
Budget allocated to HCV testing not available for other health priorities
Divert resources /timely access from those most in need (in case of testing all)

HCV: Hepatitis C virus.