Clostridioides difficile infection in liver cirrhosis patients: A population-based study in United States

Table 3 Multivariable model with Clostridioides difficile infection being the outcome

Multivariable model	Odds ratio	95%CI	P value
Age (> 65 yr vs < 65 yr)	2.307	2.179-2.442	< 0.0001
Gender (female vs male)	1.29	1.221-1.363	< 0.0001
Race (non-Caucasian vs Caucasian)	1.16	1.088-1.237	< 0.0001
Antibiotics	19.749	17.3-22.545	< 0.0001
Skilled nursing facility or inpatients	2.02	1.911-2.134	< 0.0001
Acid suppressive therapy (Proton pump inhibitors or H2 blockers)	2.243	2.122-2.371	< 0.0001
Comorbidities1	1.258	1.192-1.328	< 0.0001
Liver transplant	2.737	2.087-3.589	< 0.0001
Liver cirrhosis	1.875	1.665-2.113	< 0.0001

¹Comorbidities: One or more of the following (heart failure, coronary artery disease, chronic kidney disease, inflammatory bowel disease, chronic obstructive pulmonary disease, diabetes mellitus, obesity, hypertension or metabolic syndrome).