Prevalence and risk factors of steatosis and advanced fibrosis using transient elastography in the United States’ adolescent population

Table 6 Predictive performance of liver fibrosis indices

Liver fibrosis indices (Predictor)		Outcome	Predictive performance
Index	Cutoff		Accuracy	PPV	NPV	Sensitivity	Specificity
APRI	0.7	F4	98.45%	0%	98.8%	0.0%	99.7%
FIB4	1.3	F4	98.61%	0%	98.8%	0.0%	99.8%
PNFI	9	F4	85.31%	3.26%	99.1%	37.5%	85.9%
PNFI	3	S1-S3	85.60%	83.33%	86.2%	59.7%	95.5%

APRI: Aspartate aminotransferase to platelet ratio index; FIB4: Fibrosis-4 index; NPV: Negative predictive value; PNFI: Pediatric non-alcoholic fatty liver disease fibrosis index; PPV: Positive predictive value.