Wilson's disease: Revisiting an old friend

Table 4 Monitoring urinary copper excretion in the treatment of Wilson’s disease

Treatment	Initial treatment	Maintenance treatment	Undertreatment or non-compliance	Overtreatment or non-compliance
D penicillamine	> 500 μg/24 h	200-500 μg/24 h	> 500 μg/24 h	< 200 μg/24 h
Trientine	> 500 μg/24 h	200-500 μg/24 h	> 500 μg/24 h	< 100 μg/24 h
Zinc	> 100-500 μg/24 h	< 75 μg/24 h	> 15 μg/24 h	< 5 μg/24 h