Elderly patients (≥ 80 years) with acute calculous cholangitis have similar outcomes as non-elderly patients (< 80 years): Propensity score-matched analysis

Table 2 Clinical outcomes between elderly vs non-elderly patients

	Overall cohort, n = 457				PSM cohort, n = 224
	Elderly, n = 318	Non-elderly, n = 139	OR, 95%CI	P value	Elderly, n = 112	Non-elderly, n = 112	OR, 95%CI	P value
Initial management
ERCP	206 (64.8)	86 (61.9)	1.13 (0.75, 1.71)	0.551	77 (68.8)	65 (58)	1.59 (0.02, 2.75)	0.096
Percutaneous transhepatic biliary drainage	25 (7.9)	6 (4.3)	1.89 (0.76, 4.72)	0.166	13 (11.6)	5 (4.5)	2.81 (0.97, 8.17)	0.049
Conservative	98 (30.8)	49 (35.3)	0.82 (0.54, 1.25)	0.351	29 (25.9)	43 (38.4)	0.56 (0.32, 0.99)	0.045
Subsequent management
Index admission cholecystectomy	16 (5.0)	13 (9.4)	0.51 (0.24, 1.10)	0.081	2 (1.8)	12 (10.7)	0.15 (0.03, 0.69)	0.006
Interval cholecystectomy	20 (6.3)	11 (7.9)	0.78 (0.36, 1.68)	0.525	7 (6.3)	10 (8.9)	0.68 (0.25, 1.86)	0.449
Length of hospital stay, days	8 (6, 13)	8 (5, 11)	-	0.040	7.5 (5, 11)	8 (5, 11)	-	0.982
In-hospital mortality	16 (5.0)	5 (3.6)	1.42 (0.51, 3.96)	0.500	6 (5.4)	5 (4.5)	1.21 (0.36, 4.09)	0.757
30-d mortality	27 (8.5)	7 (5)	1.75 (0.74, 4.12)	0.195	8 (7.1)	7 (6.3)	1.15 (0.40, 3.30)	0.789
90-d mortality	31 (9.7)	8 (5.8)	1.77 (0.79, 3.95)	0.160	8 (7.1)	8 (7.1)	1.00 (0.36, 2.77)	1.000

All continuous variables were expressed as median (interquartile range) unless specified. All categorical variables were expressed as n (%) unless otherwise specified. ERCP: Endoscopic retrograde cholangiopancreatography; CI: Confidence interval; OR: Odds ratio; PSM: Propensity score matching.