Bile acid indices as biomarkers for liver diseases I: Diagnostic markers

Table 1 List of bile acid indices

Composition	Hepatic metabolism	Hydrophilicity	CYP8B1 activity	Intestinal contribution
Concentration of individual BA	Total sulfated	Total mono-OH	Total 12α-OH	Total primary
% of individual BA	Total G-amidated	Total di-OH	Total non-12α-OH	Total secondary
	Total T-amidated	Total tri-OH	12α-OH/non-12α-OH	Primary/secondary
	% Sulfation	% Mono-OH	CA/CDCA	% Primary
	% Amidation	% Di-OH	% 12α-OH	% Secondary
	% G-amidation	% Tri-OH	% Non-12α-OH
	% T-amidation

BA: Bile acids; G: Glycine; T: Taurine; CDCA: Chenodeoxycholic acid; CA: Cholic acid.