Biliary complications in recipients of living donor liver transplantation: A single-centre study

Table 10 Relation between biliary complications and mortality

Variable		Survivors (n = 141), n (%)	Non-survivors (n = 28), n (%)	OR	CI		P value1
					95% LCL	95% UCL
Biliary leakage	-	97 (85.1)	17 (14.9)	1.4	0.6	3.3	0.405
	+	44 (80)	11 (20)
Biliary infection	-	60 (83.3)	12 (16.7)	1.0	0.4	2.2	1.0002
	+	81 (83.5)	16 (16.5)
Frequency of biliary infection	Nil	60 (83.3)	12 (16.7)				0.9403
	1-2 Episodes	70 (83.3)	14 (16.7)
	≥ 3 Episodes	11 (84.6)	2 (15.4)
Early biliary infection	-	64 (82.1)	14 (17.9)	0.8	0.4	1.9	0.6552
	+	77 (84.6)	14 (15.4)
Biliary stricture	-	89 (81.7)	20 (18.3)	0.7	0.3	1.7	0.4012
	+	52 (86.7)	8 (13.3)
Frequency of biliary strictures	Nil	89 (81.7)	20 (18.3)				0.3963
	1-2 Episodes	37 (86)	6 (14)
	≥ 3 Episodes	15 (88.2)	2 (11.8)
Early biliary stricture	-	128 (83.1)	26 (16.9)	0.8	0.2	3.6	1.0002
	+	13 (86.7)	2 (13.3)
Need for ERCP	-	89 (81.7)	20 (18.3)	0.7	0.3	1.7	0.4012
	+	52 (86.7)	8 (13.3)
Frequency of ERCP	Nil	89 (81.7)	20 (18.3)				0.3753
	1-2 ERCP	36 (85.7)	6 (14.3)
	≥ 3 ERCP	16 (88.9)	2 (11.1)
Number of stents introduced for stricture	Nil	92 (82.1)	20 (17.9)				0.5203
	1-2 Stents	29 (85.3)	5 (14.7)
	≥ 3 Stents	20 (87)	3 (13)
Need for PTC	-	134 (83.2)	27 (16.8)	0.7	0.1	6.0	1.0002
	+	7 (87.5)	1 (12.5)
Frequency of PTC	Nil	134 (83.2)	27 (16.8)				0.6743
	1 PTC	7 (100)	0 (0)
	2 PTC	0 (0)	1 (100)
Surgical intervention for stricture	-	140 (83.3)	28 (16.7)				1.0002
	+	1 (100)	0 (0)
HCV PCR at occurrence of stricture	Negative	12 (80)	3 (20)				0.8493
	Below 200 000 IU	14 (93.3)	1 (6.7)
	200000 to 2 million	18 (94.7)	1 (5.3)
	More than 2 million	8 (72.7)	3 (27.3)
Antiviral treatment in relation to stricture	Not given	23 (85.2)	4 (14.8)				1.0002
	Before stricture	12 (85.7)	2 (14.3)
	After stricture	5 (83.3)	1 (16.7)
	During occurrence of stricture	12 (92.3)	1 (7.7)
Admission related to BC	-	75 (78.9)	20 (21.1)	0.5	0.2	1.1	0.0762
	+	66 (89.2)	8 (10.8)
Recurrent HCV	-	108 (84.4)	20 (15.6)	1.3	0.5	3.2	0.5602
	+	33 (80.5)	8 (19.5)
Resolution of recurrent HCV (n = 41)	-	0 (0)	4 (9.7)	9.3	3.7	23.3	0.0012
	+	33 (80.4)	4 (9.7)

¹Pearson chi-squared test unless otherwise indicated.

²Fisher’s exact test.

³Chi-squared test for trend.

Data are presented as number (n) and percentage (%). OR: Odds ratio; LCL: Lower confidence limit; UCL: Lower confidence limit; ERCP: Endoscopic retrograde cholangiopancreatography; PTC: Percutaneous transhepatic cholangiography; PCR: Polymerase chain reaction; HCV: Hepatitis C virus; BC: Biliary complication.