Tumor characteristics of hepatocellular carcinoma after direct-acting antiviral treatment for hepatitis C: Comparative analysis with antiviral therapy-naive patients

doi:10.4254/wjh.v13.i11.1743

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Nov 27, 2021; 13(11): 1743-1752
Published online Nov 27, 2021. doi: 10.4254/wjh.v13.i11.1743

Table 4 Radiological characters of hepatocellular carcinoma in both groups

	Group I	Group II	P value^c
	HCC with previous DAAs (n = 151)	HCC without previous DAAS (n = 346)
Number			< 0.001
Single	71 (47.0)	259 (74.9)
Multiple	80 (53.0)	87 (25.1)
Size			< 0.001
Less than 2 cm	1 (0.7)	54 (15.6)
2.5 cm	91(60.3)	177 (51.2)
Greater than 5 cm	59 (39.1)	115 (33.2)
Site			0.001
Bilobar	21 (13.9)	29 (8.4)
Lt lobe	24 (15.9)	23 (6.6)
RT lobe	106 (70.2)	294 (84.9)
PVT	68 (45.0)	75 (21.7)	< 0.001
Splenomegaly			< 0.001
Average	38 (25.2)	98 (28.3)
Mild	113 (74.8)	214 (61.8)
Moderate	0 (0.0)	34 (9.8)

^cP < 0.001.

HCC: Hepatocellular carcinoma; DAAs: Directly acting antiviral agents; PVT: Portal vein thrombosis.

Citation: Fouad M, El Kassas M, Ahmed E, El Sheemy R. Tumor characteristics of hepatocellular carcinoma after direct-acting antiviral treatment for hepatitis C: Comparative analysis with antiviral therapy-naive patients. World J Hepatol 2021; 13(11): 1743-1752
URL: https://www.wjgnet.com/1948-5182/full/v13/i11/1743.htm
DOI: https://dx.doi.org/10.4254/wjh.v13.i11.1743