Mitochondrial hepatopathy: Respiratory chain disorders- ‘breathing in and out of the liver’

doi:10.4254/wjh.v13.i11.1707

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Nov 27, 2021 (publication date) through Jul 28, 2024

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Nov 27, 2021; 13(11): 1707-1726
Published online Nov 27, 2021. doi: 10.4254/wjh.v13.i11.1707

Table 4 Biochemical differentiation between various metabolic hepatopathies (respiratory chain disorder vs non respiratory chain disorder comparison)

	Acidosis	Urine ketones	Blood sugar	Serum lactate	Serum ammonia
RCD	++	++	Normal	++++	±
FAOD	++	Nil (non-ketotic)	Low (hypoglycemia)	+	+
OA	+++ (persistent)	++/+++	Low/normal/high	Normal	++
UCD	Normal	Normal	Normal	Normal	++++

FAOD: Fatty acid oxidation defects; OA: Organic acidemias; RCD: Respiratory chain defects; UCD: Urea cycle defects.

Citation: Gopan A, Sarma MS. Mitochondrial hepatopathy: Respiratory chain disorders- ‘breathing in and out of the liver’. World J Hepatol 2021; 13(11): 1707-1726
URL: https://www.wjgnet.com/1948-5182/full/v13/i11/1707.htm
DOI: https://dx.doi.org/10.4254/wjh.v13.i11.1707