Copyright
©The Author(s) 2021.
World J Hepatol. Nov 27, 2021; 13(11): 1642-1652
Published online Nov 27, 2021. doi: 10.4254/wjh.v13.i11.1642
Published online Nov 27, 2021. doi: 10.4254/wjh.v13.i11.1642
Ref. | Country | Population (n) | Biochemical remission (%) | Cirrhosis (%) | Questionnaire | Factors/results |
van der Plas et al[13], 2007 | The Netherlands | AIH (142), other liver diseases (776) | - | - | SF-36, MFI-20, LDSI | HRQoL impairment; Association with: Fatigue |
Afendy et al[8], 2009 | United States, Italy | AIH (13), other chronic liver diseases (1090) | - | 84.61 | SF-36 | HRQoL impairment; Negative correlation: Age (every scale), female gender (primary predictor of mental health), cirrhosis (every scale, primary predictor of physical health) |
Schramm et al[12], 2014 | Germany | AIH (103) | 77 | 27 | SF-12, PHQ-9, GAD-7 | HRQoL impairment (total mental score/mental well-being); Association with: depression and anxiety (positive correlation with female gender, corticosteroid use, and concerns about progression of the liver disease) |
Takahashi et al[11], 2018 | Japan | AIH (265), chronic hepatitis C (88) | - | 10.6 | CLDQ, SF-36 | HRQoL impairment; Negative correlation: Age, cirrhosis, comorbid diseases, corticosteroid use (worry domain), disease duration, AST; Positive correlation: platelet count |
Wong et al[14], 2018 | United Kingdom | AIH (990) | 56 | 33 | EQ-5D-5L, FIS, CFQ, HADS | HRQoL impairment; Positive correlation: Biochemical remission; Negative correlation: overlap syndromes, corticosteroid use, and calcineurin inhibitor use |
Janik et al[15], 2019 | Poland | AIH (140) | - | 55 | SF-36, MFIS, PHQ-9, STAI | HRQoL impairment (every scale, except role emotional2); Negative correlation: Female gender, depression, trend toward better HRQoL (physical health) with budesonide vs prednisone; Association with: Anxiety, depression, and fatigue |
Dirks et al[9], 2019 | Germany | AIH (27), AIH/PBC (8), other liver diseases (97) | - | 0 | SF-36, FIS, HADS | HRQoL impairment; Association with: Anxiety, depression, and fatigue |
Castellanos-Fernández et al[7], 2021 | Cuba | AIH (22), overlap syndrome of AIH and PBC (7), PBC (14), other liver diseases (500) | - | 43.93 | FACIT-F, WPAI:SHP, CLDQ | HRQoL impairment; Positive correlation: Male gender, exercising > 90 min/wk; Negative correlation: Fatigue, abdominal pain, anxiety, depression, and extrahepatic comorbidity (diabetes mellitus type 2, sleep apnea) |
Cortesi et al[10], 2020 | Italy | AIH (51), other chronic liver diseases (2911) | - | 0 | EQ-5D-3L | HRQoL impairment in AIH |
- Citation: Snijders RJ, Milkiewicz P, Schramm C, Gevers TJ. Health-related quality of life in autoimmune hepatitis. World J Hepatol 2021; 13(11): 1642-1652
- URL: https://www.wjgnet.com/1948-5182/full/v13/i11/1642.htm
- DOI: https://dx.doi.org/10.4254/wjh.v13.i11.1642