Copyright
©The Author(s) 2021.
World J Hepatol. Oct 27, 2021; 13(10): 1428-1438
Published online Oct 27, 2021. doi: 10.4254/wjh.v13.i10.1428
Published online Oct 27, 2021. doi: 10.4254/wjh.v13.i10.1428
Variants | Hemolytic Anemia + ALF (8 patients) | Other clinical forms (44 patients) | P value | |
p.Trp939Cys (c.2817G>T) | 5 homozygotes | 6 (42.86%) | 4 (4.55%) | 0.0000 |
p.Lys844Ter (c.2530A>T) | 1 homozygotes | 4 (28.57%) | 1 (1.14%) | 0.0000 |
3 heterozygotes | ||||
p.Gly1341Asp (c.4021G>A) | 10 homozygotes | 4 (28.57%) | 23 (26.14%) | 0.8482 |
7 heterozygotes | ||||
p.His1069Gln (c.3207A>G) | 12 homozygotes | 0 | 39 (44.32%) | 0.0015 |
15 heterozygotes | ||||
Other variants | 1 homozygotes | 2 (14.29%) | 19 (21.59%) | 0.5304 |
19 heterozygotes | ||||
Total alleles | 14 (100%) | 88 (100%) |
- Citation: Pop TL, Grama A, Stefanescu AC, Willheim C, Ferenci P. Acute liver failure with hemolytic anemia in children with Wilson’s disease: Genotype-phenotype correlations? World J Hepatol 2021; 13(10): 1428-1438
- URL: https://www.wjgnet.com/1948-5182/full/v13/i10/1428.htm
- DOI: https://dx.doi.org/10.4254/wjh.v13.i10.1428