Serum zonulin levels in patients with liver cirrhosis: Prognostic implications

Table 3 Univariate analysis of factors associated to transplant free survival

Examined parameter, baseline values	Patients alive/not transplanted at the end of the follow-up, n = 54	Patients transplanted or dead, n = 9	P value
Age in yr1	59 ± 15	66 ± 14	0.238
Liver-specific treatment, Y/N	28/26	4/5	0.474
CTP score	5.9 ± 1.0	7.4 ± 1.4	< 0.001
MELD score	11.3 ± 3.0	11.7 ± 3.6	0.772
High-risk varices, Y/N	19/54	5/9	0.241
Platelet count as × 109/L	120 ± 52	109 ± 40	0.602
Albumin in g/dL	3.87 ± 0.62	3.20 ± 0.62	0.010
Spleen diameter in cm	13.7 ± 2.8	15.2 ± 2.5	0.154
Portal diameter in cm	1.27 ± 0.21	1.55 ± 0.25	0.002
Liver stiffness in kPa	22.5 ± 9.2	27.9 ± 10.3	0.127
Spleen stiffness in kPa	35.0 ± 8.8	37.9 ± 6.9	0.383
Serum zonulin levels in ng/mL	3.70 ± 1.36	3.17 ± 1.21	0.300

¹Quantitative variables are expressed as mean ± SD.

CTP: Child-Turcotte-Pugh; MELD: Model for end-stage liver disease; N: No; Y: Yes.