Serum zonulin levels in patients with liver cirrhosis: Prognostic implications

Table 2 Univariate analysis of factors associated to liver disease decompensation

Examined parameter, baseline values	Patients who remained compensated during follow-up, n = 24	Patients who proceed to decompensated disease during follow-up, n = 12	P value
Sex as M/F	13/11	3/9	0.157
Age in yr1	59 ± 12	61 ± 14	0.710
Liver-specific treatment, Y/N	13/11	9/3	0.292
High-grade varices, Y/N	6/24	6/12	0.157
Platelet count as × 109/L	138 ± 54	105 ± 46	0.094
Albumin in g/dL	3.64 ± 0.53	4.13 ± 0.51	0.013
Spleen diameter in cm	13.1 ± 2.5	14.0 ± 2.3	0.325
Portal diameter in cm	1.29 ± 0.22	1.27 ± 0.21	0.768
Liver stiffness in kPa	19.7 ± 6.9	23.9 ± 9.2	0.139
Spleen stiffness in kPa	31.1 ± 7.4	36.1 ± 9.3	0.087
Serum zonulin levels in ng/mL	3.19 ± 1.02	4.15 ± 0.95	0.011

¹Quantitative variables are expressed as mean±standard deviation.

F: Female; M: Male; N: No; Y: Yes.