Liver and COVID-19: From care of patients with liver diseases to liver injury

doi:10.4254/wjh.v13.i10.1367

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Oct 27, 2021 (publication date) through Jul 21, 2024

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Oct 27, 2021; 13(10): 1367-1377
Published online Oct 27, 2021. doi: 10.4254/wjh.v13.i10.1367

Table 1 Mechanisms of coronavirus disease 2019 liver injury

Mechanisms	Pathophysiology
Direct cytotoxicity	Active replication of SARS-CoV-2 in hepatic cells
Hyper-inflammatory reaction	Cytokine storm and activation of immune system
Systemic hypoxia	COVID-19 cardiomyopathy
Drug-induced liver injury	Liver toxicity to medication used to treat COVID-19

SARS-CoV-2: Severe acute respiratory syndrome coronavirus 2; COVID-19: Coronavirus disease 2019.

Citation: Gaspar R, Castelo Branco C, Macedo G. Liver and COVID-19: From care of patients with liver diseases to liver injury. World J Hepatol 2021; 13(10): 1367-1377
URL: https://www.wjgnet.com/1948-5182/full/v13/i10/1367.htm
DOI: https://dx.doi.org/10.4254/wjh.v13.i10.1367