Update on diagnosis and management of sepsis in cirrhosis: Current advances

Figure 3 Fasting metabolism and its impact on immune homeostasis and enhanced tolerance to infections[26-28]. The figure demonstrates the potential mechanisms associated with fasting metabolism on immune functions that ultimately prove beneficial for prevention of and combating infections. This could be hypothesized to have benefits in patients with early cirrhosis, especially in those who are obese, pending bench to bedside translational studies. Nonetheless, in advanced cirrhosis, on the contrary, nutritional management to improve immune functions, prevention of infections, and boosting tolerance to sepsis is of importance.