Update on diagnosis and management of sepsis in cirrhosis: Current advances

Figure 1 Definitions, diagnosis, and summary of prognostic scoring systems of sepsis[2,4,6,58,63-65]. Sepsis is defined as presence of suspected or confirmed infection in the presence of an organ failure as defined by the sequential organ failure assessment tool. After diagnosis of sepsis, a prognostic tool is utilized to identify patients at risk of worsening or death. APACHE: Acute physiology and chronic health evaluation; CLIF: Chronic liver failure; HeRO: Heart rate index; MBRS: Mean arterial pressure, bilirubin, respiratory failure, sepsis; MEWS: Modified early warning score; PIRO: Predisposition, insult, response, organ failure; qSOFA: Quick sequential organ failure assessment; SIRS: Systemic inflammatory response syndrome; SOFA: Sequential organ failure assessment; TREW: Targeted real-time early warning score.