Update on diagnosis and management of sepsis in cirrhosis: Current advances

Table 1 Modification of sequential organ failure assessment score for patients with cirrhosis, the chronic liver failure-sequential organ failure assessment scoring system[13,15]

Score	1	2	3	4
Respiration PaO2/FiO2 or SpO2/FiO2, mmHg	> 300 to ≤ 400 or > 357 to ≤ 512	> 200 to ≤ 300 or > 214 to ≤ 357	> 100 to ≤ 200 or 89 to ≤ 214	< 100 or ≤ 89
Liver bilirubin, mg/dL	1.2-1.9	2.0-5.9	6.0-11.9	> 12
Cardiovascular hypotension	Mean arterial pressure < 70 mmHg	Dopamine ≤ 5 or any dobutamine or terlipressin	Dopamine > 5 or noradrenaline ≤ 0.1	Dopamine > 15 or noradrenaline > 0.1
Cerebral HE grades	I	II	III	IV
Renal creatinine (mg/dL) or urine output	1.2-1.9	2.0-3.4	3.5-4.9 or use of renal replacement therapy	≥ 5.0
Coagulation - INR	≥ 1.1 to < 1.25	≥ 1.25 to < 1.5	≥ 1.5 to < 2.5	≥ 2.5 or platelet count ≤ 20000/µL

FiO₂: Fraction of inspired oxygen; HE: Hepatic encephalopathy; INR: International normalized ratio; PaO₂: Arterial oxygen pressure.