Non-alcoholic fatty liver disease is not independent risk factor for cardiovascular disease event: A cohort study

Table 2 The results of Cox proportional hazard models on fatal and non- fatal cardiovascular events as outcome, and Non-alcholic fatty liver disease, diabetes mellitus and age as potential predictors

Sex	Outcomes	Simple Cox proportional model			Multiple Cox proportional model
		Wald	HR (95% CI)	P value	Wald	HR (95% CI)	P value
NAFLD
In men	Fatal CVD events	0.963	1.345 (0.744-2.430)	0.326	0.104	0.903 (0.486-1.677)	0.747
	Non-fatal CVD events	8.400	1.606 (1.166-2.212)	0.004	3.723	1.384 (0.995-1.925)	0.054
In women	Fatal CVD events	1.570	1.694 (0.743-3.863)	0.210	0.002	1.178 (0.491-2.829)	0.714
	Non-fatal CVD events	2.327	1.416 (0.906-2.214)	0.127	0.063	0.941 (0.584-1.516)	0.802
Diabetes mellitus
In men	Fatal CVD events	37.13	6.692 (3.631-12.334)	< 0.001	8.398	2.688 (1.377-5.247)	0.004
	Non-fatal CVD events	30.98	2.999 (2.037-4.415)	< 0.001	8.789	1.885 (1.240-2.867)	< 0.001
In women	Fatal CVD events	10.99	4.034 (1.769-9.201)	< 0.001	2.165	1.867 (0.813-4.290)	0.141
	Non-fatal CVD events	40.71	4.358 (2.773-6.850)	< 0.001	14.35	2.507 (1.558-4.032)	< 0.001
Age
In men	Fatal CVD events	75.35	1.122 (1.094-1.152)	< 0.001	62.82	1.114 (1.085-1.144)	< 0.001
	Non-fatal CVD events	69.12	1.043 (1.033-1.054)	< 0.001	56.86	1.041 (1.030-1.052)	< 0.001
In women	Fatal CVD events	47.49	1.134 (1.094-1.176)	< 0.001	44.91	1.133 (1.093-1.176)	< 0.001
	Non-fatal CVD events	63.59	1.068 (1.051-1.085)	< 0.001	48.60	1.062 (1.044-1.081)	< 0.001

CI: Confidence interval; CVD: Cardiovascular disease; HR: Hazard ratio; NAFLD: Non-alcholic fatty liver disease.