Pentadecapeptide BPC 157 resolves Pringle maneuver in rats, both ischemia and reperfusion

Figure 7 BPC 157 counteracts increased serum enzymes values (IU/L, mean ± SD), gross lesions severity (liver, stomach, duodenum, jejunum, cecum, ascending colon) scored 0-4, Min/Med/max, splenomegaly (relative spleen weight as % of total body weight, mean ± SD) in ischemia, (splenomegaly appears in early reperfusion). Assessment at 30 min portal triad obstruction (PTO)-ligation time, and in reperfusion, at 15 min and 24 h reperfusion time. At 1 min post-injury (PTO-ligation time) (ischemia), or at 1 min reperfusion-time (post-PTO-ligation time) (reperfusion), medication (BPC 157, 10 μg/kg, 10 ng/kg, saline 5 mL/kg (1 mL/rat)) as a bath. ^aP < 0.05 vs saline.