Pentadecapeptide BPC 157 resolves Pringle maneuver in rats, both ischemia and reperfusion

Figure 6 BPC 157 counteracts ascites (mL) (upper), increased MDA-level (nmol/mg protein) in liver (low), in ischemia and reperfusion, and thrombus presentation (thrombus mass, g) in veins [inferior caval vein, portal vein, superior mesenteric vein, lienal vein] and artery (hepatic artery) (middle) during portal triad obstruction. Assessment at 30 min portal triad obstruction (PTO)-ligation time, and in reperfusion, at 15 min and 24 h reperfusion time, mean ± SD. At 1 min post-injury (PTO-ligation time) (ischemia), or at 1 min reperfusion-time (post-PTO-ligation time) (reperfusion), medication (BPC 157, 10 μg/kg, 10 ng/kg, saline 5 mL/kg (1 mL/rat)) as a bath. ^aP < 0.05 vs saline. ^aP < 0.05, at least vs healthy liver.