Pentadecapeptide BPC 157 resolves Pringle maneuver in rats, both ischemia and reperfusion

Figure 3 BPC 157 improves the vessels presentation during ischemia. Vessels presentation (filled/appearance or cleared out/disappearance) assessed at the stomach, and between the arcade vessels on the ventral side at 1 cm long segment of duodenum, jejunum, ascending colon, and between 10 vessels from proximal to distal cecum throughout the following experiment [with regard to the point immediately before therapy (as 100%) (A)] at selected time points before (A); and (i) after therapy (B, C, D), in rats with portal triad obstruction (PTO) at 5 (B), 15 (C) and 30 (D) min PTO-ligation time; mean ± SD. The gross appearance of the tissue was recorded using a USB microscope camera. At 1 min post-injury (PTO-ligation time), medication BPC 157, 10 μg/kg (BPC 157 μg), 10 ng/kg (BPC 157 ng), saline (Saline) 5 mL/kg (1 mL/rat) as a bath. For clarity, the SD is not shown on the graph; the SD was never higher than 10% of the mean. Presentation at the dorsal side corresponds with that on the ventral side. ^aP < 0.05 vs saline.