Copyright
©The Author(s) 2020.
World J Hepatol. May 27, 2020; 12(5): 207-219
Published online May 27, 2020. doi: 10.4254/wjh.v12.i5.207
Published online May 27, 2020. doi: 10.4254/wjh.v12.i5.207
Table 3 Histopathological patterns, R ratios and Drugs/HDS in our study
Histopathological pattern | R ratio | Total, n = 38 (%) | Drugs/HDS (n) |
Hepatitis | 12 ± 0.4 | 18 (47.4) | |
Acute | 16 ± 0.1 | 5 (13.2) | Nitrofurantoin (1) |
Black cohosh1 (1) | |||
Sertraline (1) | |||
Lamotrigine (1) | |||
Green tea extract (1) | |||
Acute with extensive necrosis | 11 ± 3.3 | 8 (21.1) | Diclofenac (1) |
Acetaminophen (6) | |||
Black cohosh1 (1) | |||
Autoimmune-like | 6.2 ± 0.1 | 3 (7.9) | Infliximab (2) |
Isoniazid (1) | |||
Chronic | 8.8 | 1 (2.6) | Nitrofurantoin (1) |
Non-necrotizing granulomatous hepatitis | 14 | 1 (2.6) | BCG (1) |
Cholestasis | 0.5 ± 0.1 | 5 (13.2) | |
Acute | 0.4 ± 0.5 | 4 (10.5) | Ceftriaxone (1) |
Methimazole (1) | |||
Total parenteral nutrition (1) | |||
Rivaroxaban (1) | |||
Chronic | 0.8 | 1 (2.6) | Triazolam and statin (1) |
Cholestatic hepatitis | 9.0 ± 5.6 | 8 (21.1) | Ezetimibe (1) |
Cefazolin (1) | |||
Hydroxycut2 (1) | |||
Rizatriptan5 (1) | |||
Methyldrostanolone (1) | |||
Trimethobenzamide Hydrochloride5 (1) | |||
Mesalamine (1) | |||
C4 extreme3 (1) | |||
Macrovesicular steatohepatitis | 1.4 ± 1.2 | 5 (13.2) | Trimethoprim-sulfamethoxazole6 (1) |
L-asparaginase (1) | |||
Valproic acid (1) | |||
Haart4 (1) | |||
Amiodarone (1) | |||
Mixed cholestatic hepatitis with steatosis and bile duct injury | 1.1 ± 0.8 | 2 (5.3) | Dronedarone6 (1) |
Hydroxycut26 (1) |
- Citation: Siddique AS, Siddique O, Einstein M, Urtasun-Sotil E, Ligato S. Drug and herbal/dietary supplements-induced liver injury: A tertiary care center experience. World J Hepatol 2020; 12(5): 207-219
- URL: https://www.wjgnet.com/1948-5182/full/v12/i5/207.htm
- DOI: https://dx.doi.org/10.4254/wjh.v12.i5.207