Interleukin-6-174G/C polymorphism is associated with a decreased risk of type 2 diabetes in patients with chronic hepatitis C virus

doi:10.4254/wjh.v12.i4.137

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Apr 27, 2020 (publication date) through Jan 10, 2025

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Apr 27, 2020; 12(4): 137-148
Published online Apr 27, 2020. doi: 10.4254/wjh.v12.i4.137

Table 2 The interleukin genotype distribution in patients with chronic hepatitis C (n = 245) and healthy controls (n = 179)

Variables	CHC, n (%)	Control, n (%)	P value
IL-6 genotypes
-174			0.81
C/C	18 (7.3)	13 (7.3)
G/C	85 (34.7)	68 (38.0)
G/G	142 (58.0)	98 (54.7)
Total	245 (100)	179 (100)
HWE (P value)	0.38	0.95

The asymptotic Pearson’s χ² test was used to compare categorical variables. P ≤ 0.05 were considered significant. n: Number of subjects; CHC: Chronic hepatitis C; IL-6: Interleukin-6; HWE: Hardy-Weinberg Equilibrium.

Citation: da Silva CB, Vieira DA, de Melo LF, Chagas ALS, Gomes AD, Faria Jr CLL, Teixeira R, de Magalhães Queiroz DM, Rocha GA, Soares MMS, Bezerra JMT, Silva LD. Interleukin-6-174G/C polymorphism is associated with a decreased risk of type 2 diabetes in patients with chronic hepatitis C virus. World J Hepatol 2020; 12(4): 137-148
URL: https://www.wjgnet.com/1948-5182/full/v12/i4/137.htm
DOI: https://dx.doi.org/10.4254/wjh.v12.i4.137