Circulating miR-21-5p level has limited prognostic value in patients with hepatocellular carcinoma and is influenced by renal function

Figure 4 Overall survival analysis in subgroups of patients in relation to hsa-miR-21-5p level. A: Survival analysis in patients with normal creatinine (divided into two groups: (1) Low: < 50^th percentile (n = 33) and (2) High: > 50^th percentile [n = 33]); B: Survival analysis in patients with pathological creatinine (hsa-miR-21-5p [miR-21] low n = 13; miR-21 high n = 12); C: Survival analysis in patients with normal alanine aminotransferase (miR-21 low n = 29; miR-21 high n = 29); D: Survival analysis in patients with pathological alanine aminotransferase (ALAT) (miR-21 low n = 17, miR-21 high n = 16); E: Survival analysis in patients with normal aspartate aminotransferase (ASAT) (miR-21 low n = 15; miR-21 high n = 15); and F: Survival analysis in patients with pathological ASAT (miR-21 low n = 31; miR-21 high n = 30). Nonparametric log-rank test was used for statistical analysis. MiR-21: Hsa-miR-21-5p.