Non-invasive splenic parameters of portal hypertension: Assessment and utility

Table 1 Baseline characteristics of the patient population

Parameter	Mean (standard deviation) or n
	Groups 1 and 2 (n = 50)	Group 1 (n = 25)	Group 2 (n = 25)
Age	57.86 (12.22)	60.44 (9.89)	55.28 (13.90)
Sex (M:F)	31:19	15:10	16:9
BMI	29.42 (7.61)	28.59 (5.76)	30.31 (9.26)
Skin to liver capsule Distance (cm)	2.43 (0.99)	2.46 (1.01)	2.40 (0.99)
METAVIR score	3.13 (1.276)	3.74 (0.752)	2.52 (1.410)
ALD	12	7	5
NAFLD	12	4	8
ALD and NAFLD	4	3	1
HCV	2	2	0
AIH	3	0	3
Miscellaneous	17	9	9
Total bilirubin (μmol/L)	28.00 (44.728)	39.92 (60.139)	16.08 (13.108)
ALP (IU/L)	127.33 (66.902)	144.56 (75.900)	109.38 (51.679)
GGT (IU/L)	147.68 (192.683)	160.96 (166.671)	134.96 (217.570)
ALT (IU/L)	60.84 (12.219)	48.52 (29.427)	73.16 (83.490)
AST (IU/L)	62.50 (49.043)	64.88 (32.720)	60.12 (61.872)
Albumin (g/L)	34.10 (6.129)	30.88 (5.761)	37.32 (4.679)
Platelet count (× 109)	151.42 (73.016)	112.16 (60.023)	190.68 (63.804)
Prothrombin time (sec)	12.572 (1.9886)	13.470 (2.2077)	11.540 (1.0007)
INR	1.184 (0.1742)	1.260 (0.1871)	1.108 (0.1222)
EGD (PH present)	25	25	0
HVPG (PH present)	5	5	0

Group 1: Population with evidence of portal hypertension; Group 2: Population with no evidence of portal hypertension. BMI: Body mass index; ALD: Aldosterone; NAFLD: Non-alcoholic fatty liver disease; HCV: Hepatitis C virus; AIH: Autoimmune hepatitis; ALP: Alkaline phosphatase; GGT: γ-glutamyl transpeptidase; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; INR: International normalized ratio; EGD: Esophago-gastroduodenoscopy; HVPG: Hepatic venous pressure gradient; PH: Portal hypertension.