PNPLA3 and TM6SF2 polymorphisms in Brazilian patients with nonalcoholic fatty liver disease

Figure 1 Relationship between the rs738409 genotype and the histological parameters. A: Prevalence of nonalcoholic steatohepatitis (NASH) P = 0.001; B: Prevalence of absent (S = 0) and mild (S = 1) steatosis or moderate (S = 2) and severe (S = 3) steatosis (P = 0.099); C: Prevalence of mild (A ≤ 2) or significant (A > 2) activity of NASH (P = 0.013); D: Prevalence of mild (A ≤ 2 and F ≤ 2) or significant (A > 2 and/or F > 2) grade of NASH based on the Steatosis, Activity, and Fibrosis score evaluation (P = 0.003); E: Prevalence of mild to moderate fibrosis (F0-F2) or advanced fibrosis (F3-F4) (P = 0.001); and F: Prevalence of fibrosis occurrence (P = 0.010). NASH: Nonalcoholic steatohepatitis.