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©The Author(s) 2020.
World J Hepatol. Oct 27, 2020; 12(10): 850-862
Published online Oct 27, 2020. doi: 10.4254/wjh.v12.i10.850
Published online Oct 27, 2020. doi: 10.4254/wjh.v12.i10.850
Table 4 Performance of the novel markers when compared to the traditional tools
| Cutoff value | PLT/SD ratio above 872 | FIB-4 above 3.25 | ABI below 0.94 | LDL/PLT ratio above 1 | CIMT above 1.1 | VLDL below 16.5 | P value |
| n | 90 | 90 | 70 | 98 | 96 | 76 | |
| LS (kPa) | 24.4 ± 6.2 | 26. 5 ± 5.2 | 22 ± 8.2 | 23 ± 7 | 24.6 ± 6.7 | 25.3 ± 6.3 | F = 1.87, P = 0.117 |
| ABI | 1.08 ± 0.09 | 1.09 ± 0.1 | 0.887 ± 0.04 | 0.93 ± 0.1 | 0.88 ± 0.1 | 0.96 ± 0.08 | F = 30, P = 0.001 |
| Endoscopy | - | - | - | - | - | - | - |
| EVs, n (%) | 82/90 (91.1) | 56/90 (62.2) | 65/70 (92.9) | 92/98 (94) | 90/96 (93.8) | 68/76 (89.5) | P = 0.001 |
| Grade I-II, n (%) | 26/32 (81.3) | 14/32 (35) | 20/32 (62.5) | 24/32 (75) | 24/32 (75) | 10/32 (31.3) | χ2 = 13.3, P = 0.009 |
| Grade III, n (%) | 32/42 (76.2) | 30/42 (71.4) | 30/42 (71.4) | 42/42 (100) | 40/42 (95) | 34/42 (81) | χ2= 7.67, P = 0.104 |
| Grade IV, n (%) | 14/16 (87.5) | 6/16 (37.5) | 9/16 (56.3) | 16/16 (100) | 16/16 (100) | 12/16 (75) | χ2= 9.55, P = 0.048 |
| Fundal varix, n (%) | 10/12 (83.3) | 6/12 (50) | 6/12 (50) | 10/12 (83) | 10/12 (83) | 12/12 (100) | χ2= 3.47,P = 0.48 |
- Citation: Hanafy AS, Basha MAK, Wadea FM. Novel markers of endothelial dysfunction in hepatitis C virus-related cirrhosis: More than a mere prediction of esophageal varices. World J Hepatol 2020; 12(10): 850-862
- URL: https://www.wjgnet.com/1948-5182/full/v12/i10/850.htm
- DOI: https://dx.doi.org/10.4254/wjh.v12.i10.850