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©The Author(s) 2020.
World J Hepatol. Oct 27, 2020; 12(10): 792-806
Published online Oct 27, 2020. doi: 10.4254/wjh.v12.i10.792
Published online Oct 27, 2020. doi: 10.4254/wjh.v12.i10.792
Table 5 Association of the PNPLA3 rs738409 genotype and activity of nonalcoholic steatohepatitis and fibrosis, adjusted for age, gender, body mass index and diabetes, evaluated by multivariate binary logistic regression analysis
Genotypes | OR | 95%CI | P value |
Activity of NASH (A > 2 vs A < 2) | |||
CC vs CG/GG | 0.65 | 0.22-1.88 | 0.433 |
CC vs GG | 17.11 | 1.87 - 156.25 | 0.012 |
Fibrosis (presence vs absence) | |||
CC vs CG/GG | 3.05 | 1.01-9.17 | 0.046 |
CC vs GG | 7.42 | 1.55-35.47 | 0.012 |
- Citation: Lisboa QC, Nardelli MJ, Pereira PA, Miranda DM, Ribeiro SN, Costa RSN, Versiani CA, Vidigal PVT, Ferrari TCA, Couto CA. PNPLA3 and TM6SF2 polymorphisms in Brazilian patients with nonalcoholic fatty liver disease. World J Hepatol 2020; 12(10): 792-806
- URL: https://www.wjgnet.com/1948-5182/full/v12/i10/792.htm
- DOI: https://dx.doi.org/10.4254/wjh.v12.i10.792