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©The Author(s) 2019.
World J Hepatol. Sep 27, 2019; 11(9): 689-700
Published online Sep 27, 2019. doi: 10.4254/wjh.v11.i9.689
Published online Sep 27, 2019. doi: 10.4254/wjh.v11.i9.689
Table 3 Univariate and multivariate Cox regression models of mortality at 30 d
Variables | Univariate Cox regression | Multivariate Cox regression | ||||
β | Relative risk (95%CI) | P value | β | Relative risk (95%CI) | P value | |
Donor | ||||||
Age | 1.03 | (0.97-1.08) | 0.28 | |||
Donor AST (IU/L) | 1 | (0.99-1.02) | 0.84 | |||
Donor ALT (IU/L) | 0.99 | (0.97–1.02) | 0.63 | |||
Donor GGT (IU/L) | 1 | (0.99–1.01) | 0.93 | |||
Epinephrine dose (mg/kg/min) | 0.03 | (0.00–5.69) | 0.93 | |||
Na levels in donor blood | 0.93 | (0.84–1.03) | 0.19 | |||
DRI | 4.49 | (0.26–76.92) | 0.3 | |||
ICU time (d) | 1.04 | (0.89–1.22) | 0.62 | |||
Recipient | ||||||
Age | 1.04 | (0.94-1,14) | 0.43 | |||
MELD | 0.88 | (0.72–1.08) | 0.22 | |||
MELD-Na | 0.98 | (0.87–1.11) | 0.76 | |||
Creatinine (mg/dL) | 1.08 | (0.52–2.26) | 0.83 | |||
AST basal (IU/L) | 1 | (1-1) | 0.03 | |||
Bilirubin basal (mg/dL) | 0.98 | (0.88–1.09) | 0.75 | |||
INR basal | 1.03 | (0.44–2.39) | 0.95 | |||
Preservation | ||||||
Cold ischaemia time (min) | 1 | (0.99–1.00) | 0.31 | |||
Hot ischaemia time (min) | 1 | (0.98–1.04) | 0.56 | |||
Total ischaemia time (min) | 1 | (0.99-1) | 0.33 | |||
Intraoperative | ||||||
Need red blood cells (units) | 1.17 | (0.91–1.50) | 0.37 | |||
Need intraoperative platelets (units) | 0.92 | (0.70–1.20) | 0.54 | |||
Need intraoperative plasma (units) | 0.93 | (0.60–1.43) | 0.74 | |||
Need intraoperative cryoprecipitate (g) | 1.1 | (0.71–1.70) | 0.68 | |||
Hepatic arterial flow (mL/min) | 0.99 | (0.97-1) | 0.01 | |||
Portal venous flow (mL/min) | 0.99 | (0.99–1.00) | 0.01 | |||
Total hepatic flow (mL/min) | 0.99 | (0.98–1.00) | 0.04 | |||
HAF < 180 mL/min | 5.9 | (1.13–30.99) | 0.04 | 5.33 | (1.01–28.22) | 0.04 |
PVF < 1200 mL/min | 5.31 | (1.02–27.70) | 0.04 | |||
INR day 1 > 2,2 | 6.07 | (1.11–33.22) | 0.04 | |||
AST day 1 > 2000 UI/dL | 10.82 | (1.26–92.97) | 0.03 | 9.856 | (1.15–84.78) | 0.04 |
- Citation: Lominchar PL, Orue-Echebarria MI, Martín L, Lisbona CJ, Salcedo MM, Olmedilla L, Sharma H, Asencio JM, López-Baena JÁ. Hepatic flow is an intraoperative predictor of early allograft dysfunction in whole-graft deceased donor liver transplantation: An observational cohort study. World J Hepatol 2019; 11(9): 689-700
- URL: https://www.wjgnet.com/1948-5182/full/v11/i9/689.htm
- DOI: https://dx.doi.org/10.4254/wjh.v11.i9.689