Prolonged high-fat-diet feeding promotes non-alcoholic fatty liver disease and alters gut microbiota in mice

Figure 1 Morphometric characterization of mice subjected to prolonged high-fat diet-feeding. A: Average body weight; B: Average mass of epididymal fat pad; C: Kidney fat pad; D: Mesenteric fat pad; E: Liver tissue; F: Spleen tissue. G: Representative hematoxylin and eosin images of epididymal adipose tissue (200 X). Data are expressed as mean ± SE. n = 15-20 mice per group. ^aSignificantly different from Young-LFD (P < 0.05). ^b Significantly different from Old-LFD (P < 0.05). HFD: High-fat diet-feeding; LFD: Low-fat diet.