Epidemiology and outcomes of acute liver failure in Australia

Table 3 Outcomes of acute liver failure managed at the Victorian Liver Transplant Unit in a historical cohort^† compared to the current series

Aetiology	TFS (%)					OS (%)
	1988-20011		2002-2017		P value	1988-20011		2002-2017		P value
	n	%	n	%		n	%	n	%
Paracetamol	20	69.0	62	73.8	0.614	21	72.4	65	77.4	0.589
Non-paracetamol	10	19.6	26	30.6	0.160	29	56.9	57	67.1	0.230
Viral hepatitis	2	18.2	10	38.4	0.228	5	45.5	18	69.2	0.173
HBV	2	25.0	7	35.0	0.609	4	50.0	14	70.0	0.318
HAV	0	0.0	3	75.0	0.047	1	0.33	3	75.0	0.270
Drug/toxin induced	3	60.0	5	29.4	0.211	4	80.0	12	70.6	0.678
Autoimmune hepatitis	0	0.0	3	33.3	-	0	0.0	6	66.7	-
Indeterminate hepatitis	5	18.5	2	9.5	0.381	15	55.5	14	66.7	0.435
Other	0	0.0	6	50.0	0.017	5	62.5	7	58.3	0.852

¹Gow et al[12], 2001. TFS: Transplant-free survival; OS: Overall hospital survival; HBV: Hepatitis B virus; HAV: Hepatitis A virus.