Nonalcoholic fatty liver disease prevalence in an Italian cohort of patients with hidradenitis suppurativa: A multi-center retrospective analysis

Table 2 Differences among hidradenitis suppurativa patients with and without diabetes

	Non diabetes	Diabetes	P value
n	62	21
Age, mean(SD)	42.44 (9.4)	41.62 (8.2)	0.722
Age cat (%)			0.203
< 30	4 ( 6.5)	3 (14.3)
> 50	17 (27.4)	3 (14.3)
30-39	20 (32.3)	4 (19.0)
40-49	21 (33.9)	11 (52.4)
Male, n (%)	21 (33.9)	10 ( 47.6)	0.387
Diabetes, n (%)	0 ( 0.0)	21 (100.0)	<0.001
BMI, mean(SD)	28.10 (2.6)	27.81 (1.4)	0.636
bmi_cat (%)			0.161
Normal Weight	8 (12.9)	0 ( 0.0)
Obese	9 (14.5)	2 ( 9.5)
Overweight	45 (72.6)	19 ( 90.5)
IHS4, mean(SD)	10.37 (3.6)	8.81 (4.1)	0.101
IHS4 cat, n (%)			0.051
Mild	4 ( 6.5)	4 ( 19.0)
Moderate	23 (37.1)	11 ( 52.4)
Severe	35 (56.5)	6 ( 28.6)
Hurley, n (%)			0.022
1	4 ( 6.5)	4 ( 19.0)
2	14 (22.6)	9 ( 42.9)
3	44 (71.0)	8 ( 38.1)
Elevated_liver_enzymes, n (%)	21 (33.9)	7 ( 33.3)	1
ADDI_score, mean(SD)	3.13 (1.8)	2.62 (2.0)	0.275
Inflammatory comorbidities, n (%)	9 (14.5)	5 ( 23.8)	0.518
In.detail, n (%)			0.563
	53 (85.5)	16 ( 76.2)
Acne conglobata	1 ( 1.6)	0 ( 0.0)
Crohn	1 ( 1.6)	1 ( 4.8)
Lichen sclerosus	0 ( 0.0)	1 ( 4.8)
PASH	4 ( 6.5)	1 ( 4.8)
Psoriasis	1 ( 1.6)	1 ( 4.8)
Spondyloarthritis	1 ( 1.6)	1 ( 4.8)
Uveitis	1 ( 1.6)	0 ( 0.0)
Positive_ultrasound, n (%)	31 (50.0)	12 ( 57.1)	0.754
NASH, n (%)	9 (14.5)	3 ( 14.3)	1
NAFL, n (%)	14 (22.6)	6 ( 28.6)	0.795
Disease, n (%)			0.853
HS only	39 (62.9)	12 ( 57.1)
NAFL	14 (22.6)	6 ( 28.6)
NASH	9 (14.5)	3 ( 14.3)

ADDI: Autoinflammatory Disease Damage Index; BMI: Body mass index; HS: Hidradenitis suppurativa; IHS4: International Hidradenitis Suppurativa Severity Scoring System; NASH: Non-alcoholic steatohepatitis; NAFL: Nonalcoholic fatty liver; PASH: Pyoderma gangrenosum, Acne, and hidradenitis suppurativa; SD: Standard deviation. Normal weight: 18.5–24.9 kg/m²; Overweight: 25-29.9 kg/m²; Obese: > 29.9 kg/m².