Angiogenesis of hepatocellular carcinoma: An immunohistochemistry study

Table 5 Correlation of the angiogenic immunophenotype, quantified with VEGF-A and COX2, with endothelial area values

	COX-2 intensity			P value	VEGF-A intensity			P value
	1+	2+	3+		1+	2+	3+
EA-CD31	8.66 ± 1.41	7.47 ± 2.29	6.76 ± 2.34	0.04	7.23 ± 1.52	7.53 ± 2.44	8.01 ± 2.32	0.72
EA-CD105	9.22 ± 1.83	9.58 ± 3.56	8.53 ± 2.64	0.53	8.45 ± 1.74	8.95 ± 3.02	10.31 ± 3.15	0.28

EA: Endothelial area; VEGF: Vascular endothelial growth factor; COX-2: Cyclooxygenase-2.