Angiogenesis of hepatocellular carcinoma: An immunohistochemistry study

Table 4 Endothelial area assessment, using CD31 and CD105 antibodies in hepatocellular carcinoma

Parameter	Number of cases	CD31-EA(median and range values)	P value		P value
				CD105-EA(median and range values)
Gender
Males	36	7.35 ± 2.16 (2.57-11.18)	0.31	8.91 ± 2.64 (4.06-15.53)	0.44
Females	14	8.06 ± 2.30 (4.17-11.85)		9.59 ± 3.28 (4.23-16.56)
Tumor grade
G1+G2	32	7.69 ± 2.22 (2.57-11.69)	0.53	9.28 ± 2.64 (4.06-16.56)	0.55
G3+G4	18	7.29 ± 2.21 (3.34-11.85)		8.78 ± 3.17 (5.77-15.53)
Tumor stage
pT1	23	7.85 ± 2.33 (2.57-11.69)	0.59	9.47 ± 3.15 (4.06-16.56)	0.39
pT2	27	7.71 ± 2.11 (3.34-11.85)		8.79 ± 2.51 (5.47-14.91)
Associated lesions
With cirrhosis	18	8.29 ± 1.68 (5.64-11.85)	0.07	9.12 ± 2.51 (4.23-14.33)	0.97
Without cirrhosis	32	7.13 ± 2.37 (2.57-11.69)		9.09 ± 3.01 (4.06-16.56)
With Mallory bodies	14	8.01 ± 1.39 (5.56-10.53)	0.36	9.86 ± 2.89 (5.85-15.53)	0.23
Without Mallory bodies	36	7.37 ± 2.44 (2.57-11.85)		8.81 ± 2.77 (4.06-16.56)
With hepatitis	24	7.28 ± 1.99 (2.57-10.53)	0.40	8.26 ± 2.25 (4.23-12.28)	0.04
Without hepatitis	26	7.80 ± 2.39 (3.07-11.85)		9.88 ± 3.09 (4.06-16.56)

EA: Endothelial area.