Hepatocellular carcinoma recurrence after liver transplantation: Risk factors, screening and clinical presentation

Table 1 Factors possibly associated with the recurrence of hepatocellular carcinoma after liver transplantation

Related to the tumor	Related to the patient	Related to the treatment
Tumor staging	Obesity	Pretransplantation:
Vascular invasion	Viral etiology	Percutaneous tumor biopsy
	HCV treatment
Differentiation’s grade		Waiting time
	NAFLD	Bridging therapy
		Peri-transplantation:
Alpha-fetoprotein		Donor’s age
Neutrophil-lymphocyte ratio		Ischemia time
		Surgical technique
		Posttransplantation:
Enhanced uptake in PET scan		Immunosuppression
		Adjuvant sorafenib
MRI findings with gadoxetic acid
Response to LRT

MRI: Magnetic resonance imaging; LRT: Locoregional therapy; HCV: Hepatitis C virus; NAFLD: Non-alcoholic fatty liver disease.