Copyright
©The Author(s) 2019.
World J Hepatol. Feb 27, 2019; 11(2): 186-198
Published online Feb 27, 2019. doi: 10.4254/wjh.v11.i2.186
Published online Feb 27, 2019. doi: 10.4254/wjh.v11.i2.186
Observed frequency | Expected frequency | Standardized value of disequilibrium(D’) | Standardized value of correlation(r2) | QUI2value | P value of QUI2 | |||||
HLA-B | HFE H63DC>G | |||||||||
C | G | C | G | C | G | |||||
07 | 16 | 2 | 14.83 | 3.17 | 0.3683 | -0.3683 | 0.0029 | 0.5728 | 0.4492 | |
08 | 12 | 1 | 10.71 | 2.29 | 0.5626 | -0.5626 | 0.0047 | 0.9396 | 0.3324 | |
13 | 3 | 1 | 3.30 | 0.70 | -0.0899 | 0.0899 | 0.0008 | 0.1547 | 0.6941 | |
14 | 10 | 0 | 8.24 | 1.76 | 1.0000 | -1.0000 | 0.0113 | 2.2471 | 0.1339 | |
15 | 17 | 0 | 14.01 | 2.99 | 1.0000 | -1.0000 | 0.0199 | 3.9669 | 0.0464 | |
18 | 10 | 0 | 8.24 | 1.76 | 1.0000 | -1.0000 | 0.0113 | 2.2471 | 0.1339 | |
27 | 2 | 2 | 3.30 | 0.70 | -0.3933 | 0.3933 | 0.0149 | 2.9586 | 0.0854 | |
35 | 17 | 4 | 17.31 | 3.69 | -0.0177 | 0.0177 | 0.0002 | 0.0345 | 0.8526 | |
37 | 1 | 2 | 2.47 | 0.53 | -0.5955 | 0.5955 | 0.0254 | 5.0617 | 0.0245 | |
38 | 3 | 0 | 2.47 | 0.53 | 1.0000 | -1.0000 | 0.0033 | 0.6500 | 0.4201 | |
39 | 4 | 2 | 4.94 | 1.06 | -0.1911 | 0.1911 | 0.0053 | 1.0582 | 0.3036 | |
40 | 3 | 0 | 2.47 | 0.53 | 1.0000 | -1.0000 | 0.0033 | 0.6500 | 0.4201 | |
41 | 3 | 0 | 2.47 | 0.53 | 1.0000 | -1.0000 | 0.0033 | 0.6500 | 0.4201 | |
42 | 1 | 0 | 0.82 | 0.18 | 1.0000 | -1.0000 | 0.0011 | 0.2145 | 0.6433 | |
44 | 8 | 11 | 15.66 | 3.34 | -0.4891 | 0.4891 | 0.11831 | 23.5443 | < 0.00001 | |
45 | 6 | 0 | 4.94 | 1.06 | 1.0000 | -1.0000 | 0.0066 | 1.3203 | 0.2505 | |
48 | 2 | 0 | 1.65 | 0.35 | 1.0000 | -1.0000 | 0.0022 | 0.4312 | 0.5114 | |
49 | 8 | 0 | 6.59 | 1.41 | 1.0000 | -1.0000 | 0.0089 | 1.7788 | 0.1823 | |
50 | 2 | 0 | 1.65 | 0.35 | 1.0000 | -1.0000 | 0.0022 | 0.4312 | 0.5114 | |
51 | 9 | 5 | 11.54 | 2.46 | -0.2199 | 0.2199 | 0.0172 | 3.4137 | 0.0647 | |
52 | 7 | 0 | 5.77 | 1.23 | 1.0000 | -1.0000 | 0.0078 | 1.5484 | 0.2134 | |
53 | 5 | 0 | 4.12 | 0.88 | 1.0000 | -1.0000 | 0.0055 | 1.0946 | 0.2955 | |
55 | 2 | 0 | 1.65 | 0.35 | 1.0000 | -1.0000 | 0.0022 | 0.4312 | 0.5114 | |
56 | 0 | 1 | 0.82 | 0.18 | -1.0000 | 1.0000 | 0.0237 | 4.7094 | 0.0300 | |
57 | 8 | 2 | 8.24 | 1.76 | -0.0293 | 0.0293 | 0.0002 | 0.0423 | 0.8371 | |
58 | 2 | 4.94 | 1.06 | -0.1911 | 0.1911 | 0.0053 | 1.0582 | 0.3036 | ||
67 | 1 | 0 | 0.82 | 0.18 | 1.0000 | -1.0000 | 0.0011 | 0.2145 | 0.6433 |
- Citation: de Campos WN, Massaro JD, Cançado ELR, Wiezel CEV, Simões AL, Teixeira AC, Souza FF, Mendes-Junior CT, Martinelli ALC, Donadi EA. Comprehensive analysis of HFE gene in hereditary hemochromatosis and in diseases associated with acquired iron overload. World J Hepatol 2019; 11(2): 186-198
- URL: https://www.wjgnet.com/1948-5182/full/v11/i2/186.htm
- DOI: https://dx.doi.org/10.4254/wjh.v11.i2.186