Observational Study
Copyright ©The Author(s) 2018.
World J Hepatol. Sep 27, 2018; 10(9): 622-628
Published online Sep 27, 2018. doi: 10.4254/wjh.v10.i9.622
Table 1 Baseline characteristics of treatment-naïve hepatitis B monoinfected adults referred to a university hospital in Zambia according to setting of hepatitis B virus diagnosis
Clinical diagnosis (n = 31)Routine diagnosis (n = 89)P value
Median age, in years37 (29-42)33 (26-41)0.15
Male sex22 (71.0)63 (70.8)0.99
Education level completed
None to 6th grade5 (16.1)3 (3.4)0.05a
7th to 12th grade14 (45.2)49 (55.1)
College12 (38.7)37 (41.6)
Lifetime alcohol abstinence13 (41.9)36 (40.9)0.92
Herbal medicine use, past month7 (31.8)14 (16.3)0.10
Body mass index
< 2523 (76.7)56 (62.9)0.35
25-305 (16.7)20 (22.5)
> 302 (6.7)13 (14.6)
HBV DNA level, IU/mL
< 204 (15.4)21 (24.7)0.12
20-199910 (38.5)42 (49.4)
2000-191994 (15.4)12 (14.1)
≥ 200008 (30.8)10 (11.8)
HBeAg positive11 (37.9)11 (14.5)0.0081
Median ALT, in U/L (IQR)22 (17-28)23 (17-36)0.82
Elevated ALT8 (32.0)36 (43.4)0.31
AST-to-platelet ratio index ≥ 2.04 (21.1)00.0021
Liver stiffness measurement in kPa
< 7.94 (25.0)45 (84.9)< 0.0011
7.9-9.52 (12.5)4 (7.6)
> 9.510 (62.5)4 (7.6)