Metabolic syndrome does not affect sustained virologic response of direct-acting antivirals while hepatitis C clearance improves hemoglobin A1c

doi:10.4254/wjh.v10.i9.612

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Sep 27, 2018; 10(9): 612-621
Published online Sep 27, 2018. doi: 10.4254/wjh.v10.i9.612

Table 4 Mean difference in hemoglobin A1c by hepatitis C virus genotype and direct acting antiviral treatment

	Average change HbA1c (SE)	P-value
HCV genotype
1a	-0.73 (0.13)	0.97
1b	-0.69 (0.20)
2	-0.79 (0.27)
3	-0.88 (0.51)
4	-0.20 (NA)
Treatment
Sofosbuvir/Simeprevir	-0.71 (0.16)	0.97
Sofosbuvir/Ribavirin	-0.77 (0.27)
PrOD	-0.66 (0.15)
Ledipasvir/Sofosbuvir	-0.80 (0.24)

HbA1c: Hemoglobin A1c; HCV: Hepatitis C virus; PrOD: Ombitasvir/Paritaprevir/Ritonavir/ Dasabuvir

Citation: Dong TS, Aby ES, Benhammou JN, Kawamoto J, Han SH, May FP, Pisegna JR. Metabolic syndrome does not affect sustained virologic response of direct-acting antivirals while hepatitis C clearance improves hemoglobin A1c. World J Hepatol 2018; 10(9): 612-621
URL: https://www.wjgnet.com/1948-5182/full/v10/i9/612.htm
DOI: https://dx.doi.org/10.4254/wjh.v10.i9.612