Amelioration of hepatotoxicity by biocleavable aminothiol chimeras of isoniazid: Design, synthesis, kinetics and pharmacological evaluation

doi:10.4254/wjh.v10.i7.496

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Jul 27, 2018 (publication date) through Nov 22, 2024

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Jul 27, 2018; 10(7): 496-508
Published online Jul 27, 2018. doi: 10.4254/wjh.v10.i7.496

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Figure 4 In vivo pharmacokinetics after oral administration of the prodrug NI (blood). NI: Prodrug of INH and N-acetyl cysteine.

Citation: Bhilare NV, Dhaneshwar SS, Mahadik KR. Amelioration of hepatotoxicity by biocleavable aminothiol chimeras of isoniazid: Design, synthesis, kinetics and pharmacological evaluation. World J Hepatol 2018; 10(7): 496-508
URL: https://www.wjgnet.com/1948-5182/full/v10/i7/496.htm
DOI: https://dx.doi.org/10.4254/wjh.v10.i7.496