MR with Gd-EOB-DTPA in assessment of liver nodules in cirrhotic patients

Figure 4 Typical case of lipid-rich hepatocellular carcinoma. A and B: The signal loss of nodule on opposed-phase compared to in-phase indicates intralesional fat; C and D: There is mild signal intensity on T2 and DWI restriction (L); E: The nodule appears hypointense in pre-contrast phase; G-J: Note the typical arterial phase hyperenhancement (G and H) followed by washout appearance in the portal venous (I) and/or delayed phase (J) that is the key diagnostic feature of HCC; K: The lesion also demonstrate hypointensity in the hepatobiliary phase; F-H: Note how the multi-arterial phase imaging (F and H) able improve the conspicuity of the HCC, especially in the late arterial phase (H). DWI: Diffusion weighted images; HCC: Hepatocellular carcinoma.