Aberrant expression of alternative isoforms of transcription factors in hepatocellular carcinoma

Figure 2 The key processes implicated in hepatocarcinogenesis that are regulated by transcription factors or their specific isoforms. TFs with stimulatory effects on these properties are depicted in green color, and TFs acting as repressors are colored in red. Sharp arrows indicate the stimulation of HCC development, and inhibition is indicated by blunt arrows. TF: Transcription factor; HCC: Hepatocellular carcinoma; EMT: Epithelial-mesenchymal transition.