Experimental bio-artificial liver: Importance of the architectural design on ammonia detoxification performance

Table 3 Functional parameters of the cylindrical shaped bio-artificial liver¹ (n = 6 independent runs)

Perfusion time	OsmB/OsmBC	Ht (%)	Hemolysis (%)	[Glucose]B/[Glucose]BC	[NH4+]B/[NH4+]BC	QNH4+ (μmol)
0 min	0.95 ± 0.05	43 ± 3	0.12 ± 0.06	0.12 ± 0.01	23.2 ± 1.2	31.1 ± 3.9
60 min	0.99 ± 0.01	42 ± 6	0.30 ± 0.08	0.81 ± 0.03	1.4 ± 0.4	31.1 ± 4.2
120 min	1.00 ± 0.01	38 ± 2	0.65 ± 0.10	0.94 ± 0.02	1.2 ± 0.2	31.3 ± 3.8

¹The cylindrical bio-artificial liver designed for liver microorgans functioning without any biological component. B: Blood; BC: Biological compartment; Ht: Hematocrit.