Ratio of mean platelet volume to platelet count is a potential surrogate marker predicting liver cirrhosis

Table 2 Multivariate analysis of factors predicting liver cirrhosis

		Odds ratio	P-value	95%CI
MPV/PLT ratio	≥ 0.71, n = 151	3.71	< 0.0001	1.94-7.28
	< 0.71, n = 151
PT, %	≥ 89.0, n = 151	2.68	0.0018	1.44-5.06
	< 89.0, n = 151
AST, IU/L	≥ 39, n = 155	3.30	0.01	1.30-9.09
	< 39, n = 147
ALT, IU/L	≥ 34, n = 153	2.57	0.04	1.02-7.09
	< 34, n = 149
Total-bilirubin, mg/dL	≥ 0.7, n = 177	1.89	0.04	1.00-3.61
	< 0.7, n = 125
Albumin, g/dL	≥ 3.8, n = 168	0.95	0.89	0.47-1.89
	< 3.8, n = 134
Cholinesterase, IU/L	≥ 211, n = 152	0.98	0.96	0.48-1.98
	< 211, n = 150
Type 4 collagen, ng/mL	≥ 6.5, n = 166	0.95	0.86	0.51-1.72
	< 6.5, n = 136
Hyaluronic acid, ng/mL	≥ 124, n = 153	2.28	0.008	1.23-4.26
	< 124, n = 149
ICGR15, %	≥ 14.3, n = 151	1.40	0.30	0.72-2.68
	< 14.3, n = 151
GSA Rmax, mg/min	≥ 0.555, n = 151	1.51	0.24	0.75-3.04
	< 0.555, n = 151

ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; CI: Confidence interval; GSA-Rmax: Maximal removal rate of 99mTc-DTPA-galactosyl human serum albumin; ICGR15: Indocyanine green retention rate at 15 min; MPV: Mean platelet volume; PLT: Platelet count; PT: Prothrombin activity.