Predicting early outcomes of liver transplantation in young children: The EARLY study

Table 4 Univariate and multiple logistic regression for the secondary outcome of any thrombosis after liver transplantation

Variable	Univariate logistic regression, n = 65		Multiple logistic regression, n = 62
	Odds ratio (95%CI)	P-value	Odds ratio (95%CI)	P-value
Yr	0.96 (0.81, 1.14)	0.656
Weight	0.74 (0.53, 1.03)	0.075
PELD	0.97 (0.93, 1.02)	0.218
Surgeon 2 vs 1	1.50 (0.37, 6.03)	0.568
Surgeon 3 vs 1	7.20 (1.75, 29.57)	0.006	8.66 (0.99, 75.63)	0.051
Surgeon 2 vs 3	0.21 (0.05, 0.88)	0.033
Surgery duration, n = 591	0.99 (0.98, 1.00)	0.017
Fascia closed on admission	2.55 (0.84, 7.78)	0.1
Hepatic artery any comment2	2.55 (0.84, 7.78)	0.1
Biliary anatomy comment2	5.12 (1.08, 24.20)	0.039
Any operating note comment	3.44 (0.99, 11.94)	0.052
Lowest anti-thrombin d2-5, n = 62	0.95 (0.91, 1.00)	0.03	0.93 (0.87, 0.99)	0.038
First day use of furosemide, n = 541	1.24 (1.04, 1.47)	0.018
Graft type R/SL vs WL	0.12 (0.03, 0.54)	0.006	0.10 (0.01, 0.85)	0.034
Graft type LR vs WL	0.10 (0.03, 0.44)	0.002	0.10 (0.01, 0.71)	0.021

¹If multiple regression is done with first day furosemide (n = 54) a trend for first day of furosemide [OR 1.37 (0.99, 1.90), P = 0.062] is found, meaning the later the furosemide is started, the higher the risk of thrombosis;

²“Any operating note comment” was used as it is collinear with “hepatic artery any comment” and “biliary anatomy comment”. If instead, we remove “any operating note comment” and add “hepatic artery any comment” and “biliary anatomy comment”, there is no meaningful change to the regression results. LR: Living related liver graft; OR: Odds ratio; PELD: Pediatric end-stage liver diseases score; R/SL: Reduced or split liver graft; WL: Whole liver graft.